Junior were the champions, winning their second title by beating Independiente Medellín 3–1 on aggregate in the final, and qualified for the 2018 Copa Libertadores.
Atlético Nacional were the defending champions, but were eliminated by Patriotas in the quarterfinals.
The 8 group winners plus the best 4 second-placed teams joined four of the teams qualified for the 2017 Copa Libertadores (Atlético Nacional, Independiente Medellín, Santa Fe, and Millonarios) in the round of 16, from where the cup continued on a home-and-away knockout basis.
Each tie in the knockout stage was played in a home-and-away two-legged format.
Atlético Nacional, Independiente Medellin, Santa Fe, and Millonarios entered the competition in the Round of 16, being joined there by the eight group winners and the four best second-placed teams.