Starting quarterback Tyrrell Pigrome was lost for the season after tearing his ACL, and senior defensive end Jessie Aniebonam will miss "several months" due to a fractured ankle.
This game marked the first start of true freshman QB Kasim Hill, and he performed very well, completing 13 of 16 passes for 163 yards with no interceptions.
It was the first time in Maryland history that the team has started a year by scoring at least 50 points in each of its first two games.
Darnell Savage added a touchdown after he intercepted a pass thrown by Towson's Ryan Stover.
Freshman tailback Javon Leake make his debut for the Terps and also got in on the big play action, scoring a touchdown after a 61-yard rush.
Maryland's last non-conference game of the season saw Central Florida visiting College Park.
In the first quarter during a QB scramble, Hill was injured, and was unable to put any weight on his right leg as he hobbled off the field with assistance.
Sophomore QB Max Bortenschlager replaced Hill, but was unable to lead the Terps to victory.
[9] The scoring was capped for the day when a Bortenschlager pass was picked off and returned for a TD by Mike Hughes.