The following expansion clubs were announced for the 2017 NPSL season: There were a number of conferences realigned for the 2017 season.
In the South Region the South Atlantic Conference was eliminated and the South Central Conference was split into the Lone Star and Heartland Conferences.
In the Midwest Region, the expanded Central Conference was renamed the North Conference and the Great Lakes East and Great Lakes West Conferences were renamed the East and Great Lakes Conferences respectively.
All playoff seeding is based on points per game.
[29] Bold = winner* = after extra time, ( ) = penalty shootout score Bold = winner* = after extra time, ( ) = penalty shootout score Bold = winner* = after extra time, ( ) = penalty shootout score Bold = winner* = after extra time, ( ) = penalty shootout score Bold = winner* = after extra time, ( ) = penalty shootout score Bold = winner* = after extra time, ( ) = penalty shootout score Bold = winner* = after extra time, ( ) = penalty shootout score Bold = winner * = after extra time, ( ) = penalty shootout score