A total of 126 weightlifters qualified to compete at the 2019 Pan American Games through scores from both the 2017 and 2018 Pan American Championships combined.

A nation may enter a maximum of 12 weightlifters (six per gender).

The host nation (Peru) automatically qualified the maximum team size.

[3] a Fernando Reis participated as an extra athlete and his results did not count for the competition.

He lifted 198 kg in Snatch for a Pan American record.