The Roadrunners played their home games at the Alamodome in San Antonio, TX, and competed in the West Division of Conference USA (C–USA).

They were led by second-year head coach Frank Wilson.

The 2017 schedule consisted of 6 home and away games in the regular season.

The Roadrunners hosted CUSA foes Marshall, Rice, Southern Miss, and UAB, and traveled to FIU, Louisiana Tech, North Texas, and UTEP.

The Roadrunners were to also host the season opener against Houston from the American Athletic Conference but the game was canceled due to Hurricane Harvey.