The 2018–19 season was Unione Sportiva Sassuolo Calcio's sixth consecutive season in the top-flight of Italian football.

The club competed in Serie A and the Coppa Italia.

Coach Giuseppe Iachini left the club on 5 June;[2] he was replaced by former Palermo and Benevento coach Roberto De Zerbi on 13 June.

[3] Last updated: 26 May 2019.

Source: Competitive matches Last updated: 26 May 2019Source: Competitions