The 2018 Delray Beach Open was a professional tennis tournament played on hard courts.

It was the 26th edition of the tournament, and part of the World Tour 250 category of the 2018 ATP World Tour.

It took place in Delray Beach, United States between February 19 and February 25, 2018.

Unseeded Frances Tiafoe, who entered the draw on a wildcard, won the singles title.

The following players received wildcards into the main draw: The following players received entry from the qualifying draw: The following players received entry as lucky losers: The following pairs received wildcards into the main draw: The following pair received entry as alternates: