The 2018 Howard Bison football team represented Howard University as a member of the Mid-Eastern Athletic Conference (MEAC) during the 2017 NCAA Division I FCS football season.

Led by Mike London in his second and final season as head coach, the Bison compiled an overall record of 4–6 with a mark of 4–3, tying for fourth place in the MEAC.

Howard played home games at William H. Greene Stadium in Washington, D.C. On November 19, London resigned to become the head coach at the College of William & Mary.

In a vote of the MEAC head coaches and sports information directors, the Bison were picked to finish in second place.

[2] The Bison had nine players at ten positions selected to the preseason all-MEAC teams.