The 2018 South Carolina State Bulldogs football team represented South Carolina State University in the 2018 NCAA Division I FCS football season.

They were a member of the Mid-Eastern Athletic Conference (MEAC).

In a vote of the MEAC head coaches and sports information directors, the Bulldogs were picked to finish in seventh place.

[1] The Tigers had four players selected to the preseason all-MEAC teams.

Despite also being members of the MEAC, games against Florida A&M and Norfolk State will be considered non-conference games and will not have an effect on the MEAC standings.