[1] Republican state senator Bob Krist announced that he would give up his party affiliation and run for governor as a Democrat.

However, after being charged with felony strangulation following an altercation with his 82-year-old father on April 8, 2018, the Nebraska Democratic Party called on him to step aside, which he did on June 25, 2018.

[14] Incumbent Republican Nebraska state treasurer Don Stenberg was term-limited and was not eligible to run for re-election to a third term.

Nebraska Public Service Commission District 3 incumbent Republican Tim Schram, who was first elected in 2006, ran for re-election to a third term.

Kara Eastman defeated Brad Ashford, who held the seat prior to losing to Bacon in 2016, in the Democratic primary.