Republican State Treasurer Mark Gordon defeated attorney Harriet Hageman, businessmen Bill Dahlin, Foster Friess, Sam Galeotos, and physician Taylor Haynes.

[1] Governor Matt Mead appointed former Speaker of the Wyoming House of Representatives Edward Buchanan to fill the remainder of Murray's term.

No candidate filed to run; however, Chris Lowry qualified for the general election by receiving enough sufficient write-in votes.

She defeated Rod Miller, a former federal land planning coordinator, and Blake Stanley for the Republican nomination.

[15] Oil geologist Greg Hunter defeated attorney Travis Helm for the Democratic nomination.