On December 12, 2017, the first day of the MLB Winter Meetings, the Padres traded Jabari Blash to the New York Yankees for Chase Headley and Bryan Mitchell.

This will be Headley's second stint with the Padres, having played with them to start his career.

To make room in the 40-man roster for both players, the Padres traded Ryan Schimpf to the Tampa Bay Rays for minor leaguer Deion Tansel.

[1] On February 19, 2018, the Padres signed free agent 1B Eric Hosmer to an 8-year, $144 million contract.

[2] Infielders Outfielders Coaches Note: G = Games played; AB = At bats; R = Runs; H = Hits; 2B = Doubles; 3B = Triples; HR = Home runs; RBI = Runs batted in; SB = Stolen bases; BB = Walks; AVG = Batting average; SLG = Slugging average Source:[1] Note: W = Wins; L = Losses; ERA = Earned run average; G = Games pitched; GS = Games started; SV = Saves; IP = Innings pitched; H = Hits allowed; R = Runs allowed; ER = Earned runs allowed; BB = Walks allowed; SO = Strikeouts Source:[2]