A total of eleven teams qualified from the Pays de la Loire preliminary rounds.
In 2018–19, Les Herbiers VF progressed furthest in the main competition, reaching the round of 32 before losing FC Villefranche.
[1] The first two rounds of the qualifying competition took place on the weekends of 25 August and 1 September 2019.
The single team from Championnat National 2 (tier 4) entered at this stage, and 42 ties were drawn.
The two teams from Championnat National (tier 3) entered at this stage, and 22 ties were drawn.