A total of eleven teams will qualify from the Pays de la Loire preliminary rounds.
[1] In 2021–22, La Roche VF progressed furthest in the main competition, reaching the round of 32, where they lost to eventual semi-finalists FC Versailles 78.
[6] The fourth round draw was made live on the leagues official Facebook page on 14 September 2022.
The fifth round draw took place on 29 September 2022, with the two teams from Championnat National joining the competition at this stage.
[8] The sixth round draw took place in an Intermarché shop in La Roche-sur-Yon on 11 October 2022.