The 2019–20 Oklahoma Sooners women's basketball team represented the University of Oklahoma in the 2019–20 NCAA Division I women's basketball season.

The Sooners were led by Sherri Coale in her twenty-fourth season.

The team played its home games at the Lloyd Noble Center in Norman, Oklahoma as a member of the Big 12 Conference.

They lost in the first round of the Big 12 women's tournament to Texas Tech.

They missed the postseason tournament for the first time since 1998 and their first losing season in 21 years.