The Sooners were led by twenty-fifth year head coach Sherri Coale.

The team played its home games at the Lloyd Noble Center in Norman, Oklahoma was a member of the Big 12 Conference.

[1] Jennie Baranczyk was announced as the new head coach in April 2021.

In the Big 12 Tournament, they lost to Oklahoma State in the Quarterfinals.

The Sooners the season 12–18, 5–13 in Big 12 play to finish in ninth place.