2019 Copa do Brasil Third Stage

If tied on aggregate, the away goals rule would not be used, extra time would not be played and the penalty shoot-out would be used to determine the winner.

[2] Host teams were settled in a draw held on 8 March 2019, 11:00 at CBF headquarters in Rio de Janeiro.

Vila Nova won 3–2 on aggregate and advanced to the fourth round.

Santa Cruz won 3–1 on aggregate and advanced to the fourth round.

Vasco da Gama won 4–2 on aggregate and advanced to the fourth round.