The 2019 season was Santa Cruz's 106th season in the club's history.

[4] Santa Cruz competed in the Campeonato Pernambucano,[5] Série C, Copa do Brasil and Copa do Nordeste.

[6] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Source: Santa Cruz official website