The 2019 East Tennessee State Buccaneers football team represented East Tennessee State University (ETSU) in the 2019 NCAA Division I FCS football season and were in the fourth year of their second stint as football members of the Southern Conference (SoCon).

They were led by second-year head coach Randy Sanders and played their home games at William B. Greene Jr. Stadium.

The Buccaneers were picked to finish in third place in both polls.

[1][2] The Buccaneers placed seven players on the preseason all-SoCon teams.

[2] Offense 1st team Quay Holmes – RB 2nd team Ben Blackmon – OL Tre'mond Shorts – OL Defense 1st team Jason Maduafokwa – DL Nasir Player – DL Tyree Robinson – DB 2nd team Jeremy Lewis – DB