The 2019 Karlsruhe Open (also known as the Liqui Moly Open Karlsruhe for sponsorship reasons) was a professional tennis tournament played on outdoor clay courts.

It was the 1st edition of the tournament and part of the 2019 WTA 125K series, offering a total of $125,000 in prize money.

It took place in Karlsruhe, Germany between 29 July and 4 August 2019.

[1] The following players received a wildcard into the singles main draw: The following players qualified into the singles main draw: The following player received entry into the main draw as a lucky loser: The following pair received a wildcard into the doubles main draw: