The 2019 Lafayette Leopards football team represented Lafayette College in the 2019 NCAA Division I FCS football season.

The Leopards were led by third-year head coach John Garrett and played their home games at Fisher Field.

The Patriot League released their preseason coaches' poll on July 30, 2019 (voting was by conference head coaches and sports information directors).

[1] The Leopards had four players selected to the preseason All-Patriot League team.

[1] Offense Nick Pearson – WR Jake Marotti – OL Defense Malik Hamm – DL Yasir Thomas – DB