The 2019 Los Cabos Open (also known as the Abierto Mexicano de Tenis Mifel presentado por Cinemex for sponsorship reasons) was an ATP tennis tournament played on outdoor hard courts.

It was the 4th edition of the tournament, and part of the ATP Tour 250 series of the 2019 ATP Tour.

It took place in Los Cabos, Mexico from July 29 through August 4, 2019.

[1] The following players received wildcards into the singles main draw: The following players received entry using a protected ranking into the singles main draw: The following players received entry from the qualifying draw: The following pairs received wildcards into the doubles main draw: