The 2019 St. Petersburg Open was a tennis tournament played on indoor hard courts.

It was the 24th edition of the St. Petersburg Open, and part of the ATP Tour 250 Series of the 2019 ATP Tour.

It took place at the Sibur Arena in Saint Petersburg, Russia, from September 16 through 22, 2019.

[1] The following players received wildcards into the singles main draw: The following players received entry using a protected ranking into the main draw: The following players received entry from the qualifying draw: The following players received entry as lucky losers: The following pairs received wildcards into the doubles main draw: