The team played in the Fargodome in Fargo, North Dakota, for the 27th season as members of the Missouri Valley Football Conference (MVFC).

They entered the season as defending national champions, having won seven of the prior eight FCS titles.

They received an automatic qualifying bid to the FCS playoff tournament and were seeded as the No.

[1] In the MVFC preseason poll released on July 29, 2019, the Bison were predicted to finish in first place.

[3] Offense Zack Johnson – OL Dillon Radunz – OL Defense Derrek Tuszka – DL Jabril Cox – LB James Hendricks – DB Garret Wegner – P