The 2020–21 Grand Canyon Antelopes men's basketball team represented Grand Canyon University during the 2020–21 NCAA Division I men's basketball season.

They were led by first-year head coach Bryce Drew and played their home games at GCU Arena in Phoenix, Arizona as members of the Western Athletic Conference (WAC).

They defeated Seattle[1] and New Mexico State[2] to win the WAC tournament and received the conference's automatic bid to the NCAA tournament where they lost in the first round to Iowa.

[4] On March 13, 2020, the school fired Dan Majerle as head coach of the Antelopes.

[5] A few days later, the school named former Vanderbilt and Valparaiso head coach Bryce Drew as the Antelopes' next head coach.