The 2020–21 BBL season was the 44th season for the London Lions in the BBL, and 9th under the banner of London Lions.

The Lions play their home games at the 6,000 seat Copper Box Arena in Queen Elizabeth Olympic Park, London.

Note: Flags indicate national team eligibility at FIBA-sanctioned events.

Players may hold other non-FIBA nationalities not displayed.

*Note: FIBA has withdrawn the London Lions from the FIBA Europe Cup Regular Season due to COVID-19 disruptions.