The 2020 Eastern Kentucky Colonels football team represented Eastern Kentucky University during the 2020–21 NCAA Division I FCS football season.

They were led by Walt Wells in his first season as the program's 15th head coach.

[1] The Colonels played their home games at Roy Kidd Stadium and competed as a member of the Ohio Valley Conference.

While the Ohio Valley Conference moved conference games to the spring of 2021, due to the COVID-19 pandemic, while allowing member schools to play four non-conference games in the fall of 2020, Eastern Kentucky scheduled eight non-conference games for the fall of 2020.

[2] [4] at Joan C. Edwards Stadium • Huntington, West Virginia at Roy Kidd Stadium, Richmond, Kentucky EKU – Matt Wilcox Jr. 10-yard pass from Parker McKinney (Alexander Woznick kick), 1:32.