The 2020 Mississippi State Bulldogs softball team represented Mississippi State University in the 2020 NCAA Division I softball season.

The Bulldogs played their home games at Nusz Park.

The Bulldogs went 2–2 in the Seattle Regional during the 2019 NCAA Division I softball tournament.

The SEC preseason poll was released on January 15, 2020.

[2] *Rankings are based on the team's current ranking in the NFCA poll.