On March 12, 2020, MLB announced that because of the ongoing COVID-19 pandemic, the start of the regular season would be delayed by at least two weeks in addition to the remainder of spring training being cancelled.

[1] Four days later, it was announced that the start of the season would be pushed back indefinitely due to the recommendation made by the CDC to restrict events of more than 50 people for eight weeks.

[4] On September 13, the Padres won their 31st game of the season, ensuring that they would finish with a winning record for the first time since 2010.

The Padres were defeated by the eventual World Series champions Los Angeles Dodgers in the NLDS at Globe Life Field.

In the 6th inning, Nola made it 6–4 with a sacrifice fly that ended in a double play as Jake Cronenworth was tagged out at 3rd.

Cardinals starter Adam Wainwright did not fare well either, as he loaded the bases in the 4th inning with nobody out, and Wil Myers would ground into a force play to get the Padres on the board.

The Padres took their first lead of the series in the bottom of the 7th when Myers homered and Tatis hit his 2nd home run of the night.

Goldschmidt though, would add another home run before Padres closer Trevor Rosenthal shut the door and sent the series to a winner take all Game 3.

Dodgers pitcher Walker Buehler started Game 1, while the Padres gave the ball to Mike Clevinger.

The Dodgers would respond in the 5th inning when Jake Cronenworth made a throwing error that scored Justin Turner.

Corey Seager hit a sacrifice fly that gave the Dodgers the lead, then Turner singled in Betts.

Dodgers reliever Joe Kelly then shut the door after that and put the Padres in an 0-2 NLDS hole The Dodgers gave the ball to flame-throwing right hander Dustin May, while the Padres gave the ball to rookie left hander Adrián Morejón.

The Dodgers broke it open in the top of the 3rd when shortstop Corey Seager drove in right fielder Mookie Betts, third baseman Justin Turner drove in Seager, left fielder A. J. Pollock singled in Turner & designated hitter Joc Pederson singled in Pollock to make it 6–2.