The 2021–22 Cal State Fullerton Titans men's basketball team represented California State University, Fullerton in the 2021–22 NCAA Division I men's basketball season.

The Titans, led by ninth-year head coach Dedrique Taylor, played their home games at Titan Gym as members of the Big West Conference.

2 seed, they defeated UC Davis, Hawaii, and Long Beach State to be champions of the Big West tournament.

They received the conference’s automatic bid to the NCAA tournament as the No.

The Big West Conference tournament was cancelled due to the COVID-19 pandemic, ending the Titans season.