2021–22 Genoa CFC season

In addition to the domestic league, Genoa participated in this season's edition of the Coppa Italia.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Win Draw Loss Fixtures Source: Soccerway Source: Serie A The league fixtures were announced on 14 July 2021.