The season started on 20 September 2021 and ended on 3 July 2022, with the relegation play-off held on 10 September 2022.
[1] Al-Shorta secured the title with seven rounds of the league remaining, setting a new record for the earliest title win in Iraq and finishing a record 21 points clear at the top of the table.
Al-Shorta also became the first club to beat all other teams in a 20-team season and the first club to win all Baghdad derbies home and away in one season.
Al-Shorta forward Mahmoud Al-Mawas from Syria became the first non-Iraqi player to win the league's top scorer award, scoring 22 goals, and the club's Egyptian manager Moamen Soliman became the first manager from Africa to win the Iraqi Premier League.
[2] Duhok are promoted to the Iraqi Premier League, while Amanat Baghdad are relegated to the Iraqi First Division League.