The Lady Rebels were led by second-year head coach Lindy La Rocque.

They played their home games at the Cox Pavilion, attached to the Thomas & Mack Center on UNLV's main campus in Paradise, Nevada.

[1] They went on to win the Mountain West women's tournament over Colorado State.

[2] They lost to Arizona as a 13-seed in the Greensboro region of the first round of the NCAA tournament.

[3] Roster Last update: March 19, 2022 2021–22 UNLV Runnin' Rebels basketball team