On 27 June, Al-Hilal secured their eighteenth league title in the final matchday following a 2–1 home win against Al-Faisaly.
[9] In the final matchday, both Al-Faisaly and Al-Ahli were relegated following a defeat to Al-Hilal and a draw with Al-Shabab respectively.
On 8 August 2021, the Saudi Professional League announced that they had signed a sponsorship deal with real estate company Roshn.
Al-Hazem will play in the top flight of Saudi football after a season's absence.
[15] Al-Fayha will play in the top flight of Saudi football after a season's absence.
[16] Al-Tai will play in the top flight of Saudi football for the first time since the 2007–08 season.
[17] In the final matchday, both Al-Qadsiah and Al-Wehda were relegated following a draw with Abha and a loss against Al-Shabab respectively.