The selection panel for the 2021 AFL Women's All-Australian team consisted of chairwoman Nicole Livingstone, Steve Hocking, Josh Vanderloo, Kelli Underwood, Sarah Black, Tim Harrington, Shelley Ware, Sharelle McMahon, Courtney Cramey and Melissa Hickey.
Collingwood had the most players selected in the initial squad with six, and every team had at least one representative.
Six players achieved selection for the first time, while seven players from the 2020 team were selected, two of whom – Melbourne vice-captain Karen Paxman and North Melbourne captain Emma Kearney – achieved selection for the fifth consecutive year.
Collingwood co-captain Brianna Davey was announced as the All-Australian captain and Fremantle midfielder Kiara Bowers was announced as the vice-captain.
[1] Note: the position of coach in the AFL Women's All-Australian team is traditionally awarded to the coach of the premiership-winning team.