Contested by 13 clubs, it operates on a system of promotion and relegation with Cambodian Second League.
[2] Boeung Ket are the defending champions, while Prey Veng makes its debut as the promoted team from the 2020 Cambodian Second League.
[3][4] The number of foreign players is restricted to five per team.
A team can use four foreign players on the field in each game, including at least one player from the AFC region.
*Note: Electricite du Cambodge do not use foreign players.