2022 CONCACAF U-20 Championship qualifying took place between 5–13 November 2021 in Santo Domingo, Dominican Republic.

The teams compete for four of the twenty berths in the 2022 CONCACAF U-20 Championship final tournament.

The highest-ranked 16 entrants were exempt from qualifying and advanced directly to the group stage of the final tournament, while the lowest-ranked 18 entrants participated in qualifying, where the four group winners advanced to the round of 16 of the knockout stage of the final tournament.

[3] The draw for the qualifying round took place on 17 September 2021, 11:00 EST (UTC−4), at the CONCACAF Headquarters in Miami.

[6] The winners of each group qualified for the 2022 CONCACAF U-20 Championship, where they enter the round of 16 of the knockout stage.