[2] The defending champions were Chinese Super League side Shandong Taishan.
They retained the trophy, beating Shanghai Port 1–0 in the final.
[4] The draw for the fourth round was held on 29 September 2021.
[5] The final was played on 9 January 2022 in Chengdu.
Assistant referees: Wang Dexin Shi Xiang Fourth official: Zhang Lei Video assistant referee: Shi Zhenlu Assistant video assistant referees: Tang Shunqi