The 2021 Montana Grizzlies football team represented the University of Montana as a member of the Big Sky Conference during the 2021 NCAA Division I FCS football season.

The Grizzlies were led by 11th-year head coach Bobby Hauck and played their home games at Washington–Grizzly Stadium in Missoula, Montana.

On July 26, 2021, during the virtual Big Sky Kickoff, the Grizzlies were predicted to finish second in the Big Sky by both the coaches and media.

[1] The Grizzlies had five players selected to the preseason all-Big Sky team.

[2] Offense Samuel Akem – WR Conlan Beaver – OT Defense Jace Lewis – LB Robby Hauck – S Special teams Matthew O'Donoghue – LS