Racing Louisville FC was announced on October 22, 2019, as an NWSL expansion team set to begin play in the 2021 season.

The opening match, a 2–2 draw against Orlando Pride, was the club's first at their home ground, Lynn Family Stadium.

With two draws and two losses in four group matches, Racing finished at the bottom of East Division in their first Challenge Cup.

[8] Racing Louisville and Chicago Red Stars from NWSL were joined by Paris Saint-Germain Féminine and FC Bayern Munich.

Racing Louisville prevailed in an 11-round shootout, after backup goalkeeper Katie Lund converted her spot kick and saved the attempt by her counterpart, Laura Benkarth.