The 2021 Rio Grande Valley FC Toros season was the 6th season for Rio Grande Valley FC Toros in USL Championship (USLC), the second-tier professional soccer league in the United States and Canada.

[1] This article covers the period from November 2, 2020, the day after the 2020 USLC Playoff Final, to the conclusion of the 2021 USLC Playoff Final, scheduled for November 28, 2021.

[2] Note: Flags indicate national team as defined under FIFA eligibility rules.

Players may hold more than one non-FIFA nationality.

2021 U.S. Open Cup was cancelled due to the COVID-19 Pandemic Numbers after plus-sign(+) denote appearances as a substitute.