The 2021 OKC Energy FC season was the club's eighth and final season of existence, and their eight consecutive season in the USL Championship, the second tier of American soccer.

The season covers the period from October 3, 2020, to the beginning of the 2022 USLC season.

The 2021 season was the second for OKC coach John Pascarella.

On June 4, 2021, following a winless start to the 2021 USL Championship season, Pascarella and the OKC Energy mutually agreed to part ways.

[1] Source: USLC standings Source: Energy FC stats Source: Energy FC stats Source: Energy FC stats