The 2021 Virginia Tech Hokies baseball team represented Virginia Tech during the 2021 NCAA Division I baseball season.

The Hokies played their home games at English Field as a member of the Atlantic Coast Conference.

They were led by head coach John Szefc, in his 4th season at Virginia Tech.

The 2020 Virginia Tech Hokies baseball team notched a 11–5 (1–2) regular season record.

The season prematurely ended on March 12, 2020, due to concerns over the COVID-19 pandemic.