The 2022–23 Marquette Golden Eagles women's basketball team represented Marquette University in the 2022–23 NCAA Division I women's basketball season.

The Golden Eagles, led by fourth year head coach Megan Duffy, played their home games at the Al McGuire Center and are members of the Big East Conference.

On February 8, 2023, the Golden Eagles defeated the UConn Huskies for the first time in program history, ending an all-time 0-16 losing streak.

It was the first time since 1993 that UConn lost two games in a row, ending a 1,083 game streak without back-to-back losses.

They defeated DePaul in the quarterfinals of the Big East women's tournament before losing to UConn in the semifinals.