On 30 May, Motherwell confirmed a week-long training camp in Obertraun, Austria, between 3 and 10 July in the lead up to their 2022–23 UEFA Europa Conference League Second qualifying round matches.

[4] On 11 July, Motherwell announced the signing of Josh Morris, on a free transfer from Salford City, to a two-year contract.

[7] On 29 July, manager Graham Alexander and his assistant Chris Lucketti left the club by mutual consent, with Steven Hammell being placed in temporary charge.

[9] On 13 August, Motherwell announced the signing of Aston Oxborough to a two-year contract, after he'd left Norwich City at the end of the previous season.

[10] On 17 August, Motherwell announced the return of Stuart McKinstry to the club, on a season-long loan deal from Leeds United.

[27] On 19 December, Motherwell announced the signing of Shane Blaney from Sligo Rovers to a two-and-a-half-year contract, starting 1 January 2023.

[40] On 31 January, Sondre Johansen left the club to sign for Odd for an undisclosed fee,[41] and Connor Shields joined Queen of the South on loan for the remainder of the season.

[47] On 11 February, Steven Hammell left his role as Head Coach of Motherwell, with Stuart Kettlewell being placed in temporary charge.

[51] On 31 May, Motherwell announced that Josh Morris had been released from his contract early, and that negotiations for new contracts where taking place with Jake Carroll, Logan Dunachie, Daniel Hunter, Kian Speirs, Jack Aitchison, Matthew Connelly, Max Johnston, Ewan Wilson, Dan Casey, Dean Cornelius, Sean Goss, Mikael Mandron, David Devine and Corey O’Donnell.