5 teams that are National Police Commissary, Asia Euro United, Electricite du Cambodge, Prey Veng, and Soltilo Angkor are relegated to the Cambodian League 2 because they did not fulfill the Cambodian Football League Company's requirements.
Cambodian dual nationals do not take up foreign players quota.
The second-round date will be announced after all first-round matches are played.
Some matches will be updated (H) – Home team(A) – Away team sheets After Angkor Tiger supporters threw bottles at the referee in protest of his choice not to award a penalty to their teams against Preah Khan Reach Svay Rieng on Matchday 13, they were prohibited from competing at their home stadium.
The decision was overturned, however, as Angkor Tiger was permitted to play in their home stadium but spectators were prohibited from attending and the clubs were required to pay a fine.