The 2022 Daytona 500 was the first stock car race of the 2022 NASCAR Cup Series and the 64th running of the event.

Team Penske dedicated their Daytona 500 win to legendary sportscaster Bob Jenkins after the race.

[15] The standard track at Daytona International Speedway is a four-turn superspeedway that is 2.5 miles (4.0 km) long.

[17] However, it was later announced on March 8 that Austin Cindric's exact winning car would be displayed at the Hall of Fame.

Michael McDowell was the fastest in the first practice session with a time of 46.696 seconds and a speed of 192.736 mph (310.179 km/h).

[22] Harrison Burton was the fastest in the final practice session with a time of 47.782 seconds and a speed of 188.355 mph (303.128 km/h).

[23] Starting in 3rd place, Brad Keselowski took the lead from Kyle Larson and Alex Bowman and led the first lap of the race.

During green flag pitstops on lap 39, Jacques Villeneuve, making his first Daytona 500 start, spun coming to pit road and was able to keep the car going and no caution was thrown.

The first caution flew on lap 41 when Kaz Grala's right rear wheel came off and Chase Briscoe got turned by Austin Cindric.

It started when Tyler Reddick got turned by Jacques Villeneuve collecting Martin Truex Jr., Joey Logano, and Kurt Busch.

[26] Jamie Little, Regan Smith and Vince Welch handled pit road for the television side.

1992 and 1998 Daytona 500 winning crew chief Larry McReynolds provided insight from the Fox Sports studio in Charlotte.

The booth crew consists of Alex Hayden, Jeff Striegle, and 1989 Cup Series champion Rusty Wallace.

On pit road, MRN was manned by Steve Post, Kim Coon, and Dillon Welch.