[2] This was also the first time in Major League history that playoff rounds overlapped, as the 2022 ALDS had a game the same day the NLCS began.

In the ninth, a potential game-ending double play was spoiled when Bryson Stott missed a throw by third baseman Alec Bohm after a Juan Soto grounder.

However, after a Manny Machado flyout, José Alvarado struck out Josh Bell to end the inning and the game.

The Padres answered back in the bottom of the inning with home runs on back-to-back pitches from Brandon Drury and Josh Bell off of Phillies starter Aaron Nola.

In the top of the fourth, with runners at first and third, San Diego's Jake Cronenworth hit a ground ball to shortstop Bryson Stott.

Stott threw to second baseman Jean Segura, who dropped the ball, allowing Juan Soto to score and tying the game at one.

In the fifth inning, San Diego's Trent Grisham hit a ground ball along the first base line that was misplayed by Rhys Hoskins for a double.

In the sixth inning, Bohm doubled to Soto, who dove for the ball and missed, scoring Nick Castellanos from second to raise the Phillies' lead by one.

In the first inning, Manny Machado hit a solo home run, followed by a two-run double by Brandon Drury that pulled Philadelphia starter Bailey Falter out of the game.

His replacement, Connor Brogdon, gave up a single by Ha-seong Kim that scored Drury to widen the Padres' lead to 4–0.

Kyle Schwarber and J. T. Realmuto added to the scoring with solo home runs in the sixth and seventh innings off Luis Garcia and Steven Wilson, respectively.

The Padres prevented additional scoring after a J. T. Realmuto single when Bryce Harper flew out to end the inning.

With two outs and two strikes on the batter, Trent Grisham, Domínguez threw another pitch in the dirt to score Azócar and give San Diego the lead.

After Domínguez's disappointing performance in the seventh inning, he was replaced with José Alvarado, who walked Soto after giving up a single to Jurickson Profar.

Scott Franzke, calling the game on Phillies radio, termed the home fans' delirious reaction "bedlam at the Bank.

This turned out to be the last postseason game for the Padres under owner Peter Seidler, who passed away at the age of 63 shortly after the 2023 season.

Seidler was credited for elevating the Padres to national prominence after years in the doldrums with financial commitments in the hundreds of millions in hopes to bring San Diego its first sports championship.