The league started on 2 April 2022, and is scheduled to end on 29 October 2022, not including play-off matches.
Mjøndalen, Stabæk, and Brann were relegated from the 2021 Eliteserien, while Kongsvinger and Skeid were promoted from the 2021 2. divisjon.
The teams from third to sixth place will take part in the promotion play-offs; these are single leg knockout matches.
The winner of the second round will meet the third-placed team on away ground.
[4] The 14th-placed team took part in a two-legged play-off against the winners of the Second Division play-offs, to decide who would play in the First Division next season.