Arjo Atayde, Ralph Tulfo, Franz Pumaren, Marvin Rillo, PM Vargas and Marivic Co-Pilar were elected to represent the city's first, second, third, fourth, fifth and sixth legislative districts respectively in the 19th Congress.

Incumbent Mayor Joy Belmonte is running for her second term against Anakalugusan party-list representative Mike Defensor.

[1][2] Vice Mayor Gian Sotto is running for his second term against incumbent second district Councilor Winnie Castelo.

[3] In the congressional race, four incumbent representatives, Anthony Peter Crisologo, Precious Hipolito-Castelo, Allan Benedict Reyes and Bong Suntay are running for reelection in the 1st, 2nd, 3rd and 4th districts respectively.

[13] Belmonte faced a challenge from eight other candidates; including representative Mike Defensor of the Malayang Quezon City coalition.

Incumbent Gian Sotto is running for his second term, facing his distant relative, former 2nd district representative and councilor Winnie Castelo and two other candidates.

Incumbent Anthony Peter "Onyx" Crisologo was defeated by actor Arjo Atayde in his reelection bid.

Lin was originally nominated by Lakas–CMD but she later resigned from the party on November 19, 2021 after her name was embroiled in the Pharmally Pharmaceutical scandal.